Project
Part:BBa_K3218007:Design
Designed by: Abraham Grosman Group: iGEM19_MSP-Maastricht (2019-10-16)
Human AID
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000INCOMPATIBLE WITH RFC[1000]Illegal BsaI.rc site found at 76
Illegal SapI site found at 177
Design Notes
Some design considerations were how close the AID would be to the target locus of our choice and what is the area containing the most mutations
Source
Human lymphocytes use this gene during B cell antibody affinity maturation.